Changing Paradigms in Ovarion Cancer Surgery & Growing Role of Peritonectomy and HIPEC

A lady of 62 years age was diagnosed with stage 3 ovarian cancer. She had peritoneal disease along with ovarian disease. She was given chemotherapy first to reduce the size of the disease. We performed aggressive cytoreducve surgery with total peritonectomy in this paent.

Later inj cisplan 100mg was circulated within abdominal cavity at 41 degree Celsius for 90 minutes (HIPEC) with the help of an indigenously designed machine by us. The overall duraon of surgery was 8 hours. Overall blood loss was 1 litre.

She required ICU for 1 day post-operavely. We also administered post-operave chemotherapy (cisplan & doxorubicin) within peritoneal cavity through the drains from post-operave days 3 to 7. She recovered well in 8 next days without any significant post-operave complicaons. Tradionally such paents used to be subjected to only debulking surgery where some amount of gross disease used to be le behind to be taken care of by further chemotherapy. This lead to higher recurrence rates within peritoneum.

But in last 1 decade, a more aggressive form of surgery called total peritonectomy & hyper thermic intra-operave intra peritoneal chemotherapy (HIPEC) has developed which results in beer survival & cure rates.